An Efficient and Novel Regioselective Synthesis of Phosphonylpyrazoles from Vinylazides and Bestmann-Ohira Reagent

被引：10

作者：

Madugula, Aravinda Kumar ^{[1
]}

Mahendran, Vaithiyanathan ^{[2
]}

Sridhara, Ajjanna Mahalingappa ^{[3
]}

Rangaiah, Gururaja ^{[1
]}

机构：

[1] PRIST Univ, Ctr Res & Dev, Thanjavur 613403, Tamil Nadu, India

[2] Madurai Kamaraj Univ, Dept Organ Chem, Madurai 625021, Tamil Nadu, India

[3] Gomti Life Sci India Pvt Ltd, Bidadi Ind Area, Bangalore 562109, Karnataka, India

来源：

ORIENTAL JOURNAL OF CHEMISTRY | 2016年 / 32卷 / 05期

关键词：

Phosphonylpyrazoles; Vinylazides; 1,3-dipolar cycloaddition; Regioselectivity; Bestmann-Ohira reagent;

D O I：

10.13005/ojc/320524

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A novel and efficient reaction of vinyl azides with Bestmann-Ohira reagent for the regioselective synthesis of phosphonylpyrazoles is presented. Reaction proceeds through 1, 3 dipolar cycloaddition with an excellent yield in short period of time under mild reaction conditions. Moreover, no column purification is involved for the isolation of products.

引用

页码：2533 / 2541

页数：9

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