Oral melanoma - Case reports and review of the literature

被引:38
|
作者
Manganaro, AM
Hammond, HL
Dalton, MJ
Williams, TP
机构
[1] UNIV IOWA,BROOKE ARMY MED CTR,DEPT ORAL & MAXILLOFACIAL SURG,IOWA CITY,IA 52242
[2] UNIV IOWA,BROOKE ARMY MED CTR,DEPT ANAT PATHOL,IOWA CITY,IA 52242
[3] UNIV IOWA,BROOKE ARMY MED CTR,COLL DENT,DEPT SURG ORAL PATHOL,IOWA CITY,IA 52242
关键词
D O I
10.1016/S1079-2104(05)80250-1
中图分类号
R78 [口腔科学];
学科分类号
1003 ;
摘要
Oral melanomas occur most often on the palate and gingiva with the maxillary arch affected 80% of the time. Melanosis may exist many years before a definitive biopsy. tong-standing lesions may ulcerate but lack rolled borders or induration, features commonly associated with squamous cell carcinoma. Melanoma that involves oral mucosa is rare with an extremely poor prognosis. Surgical management remains the preferred treatment in combination with chemotherapy. irradiation therapy is used occasionally as a primary modality in the elderly and medically compromised patients. Lymph node dissection is not routinely practiced. The poor prognosis oi oral melanomas requires that pigmented lesions of undetermined origin be routinely biopsied.
引用
收藏
页码:670 / 676
页数:7
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