DELETIONS, INSERTIONS AND REARRANGEMENTS AFFECTING RPOB GENE-EXPRESSION

Through cloning and deletion experiments on ColE1 hybrids the rpoB gene (Rifr) was located on a physical restriction map; RNA polymerase binding studies showed no binding site between rpoB and the adjacent L7/L12 ribosomal protein gene, but showed a strong binding site within the structural gene. The genetic data and RNA polymerase binding studies lead to the conclusion that rplL and rpoB are dependent upon a common promoter. © 1979 Springer-Verlag.