The Effectiveness of Botulinum Toxin Type A Injections in the Management of Sialorrhea

被引:9
|
作者
Surmelioglu, Ozgur [1 ]
Dagkiran, Muhammed [1 ]
Tuncer, Ulku [1 ]
Ozdemir, Suleyman [1 ]
Tarkan, Ozgur [1 ]
Cetik, Fikret [1 ]
Kiroglu, Mete [1 ]
机构
[1] Cukurova Univ, Sch Med, Dept Otorhinolaryngol, Adana, Turkey
关键词
Sialorrhea; botulinum toxin; parotid gland; submandibular gland; cerebral palsy;
D O I
10.5152/tao.2018.2411
中图分类号
R76 [耳鼻咽喉科学];
学科分类号
100213 ;
摘要
Objective: The aim of this study was to evaluate the effect of Botulinum toxin type A by injecting in the submandibular and parotid glands on the frequency and severity of sialorrhea. Methods: Pediatric patients who were referred to our department with sialorrhea were evaluated using their parents' frequency and severity scores of sialorrhea with visual analog scales before and after 3 months of botulinum toxin type A injections. Bilateral submandibular and parotid glands were injected with Botulinum toxin type A. Results: Twenty-seven pediatric patients who were referred to our department with a complaint of sialorrhea were included in this study. Seventeen patients were female and 10 were male. Severe sialorrhea with cerebral palsy was present in all the patients. There were no complications after the procedure. Conclusion: Botulinum toxin A injected in the major salivary glands in pediatric patients with neurological disorders is a safe and effective method.
引用
收藏
页码:111 / 113
页数:3
相关论文
共 50 条
  • [1] Clinical effectiveness of Botulinum Toxin (BoTN) injections in patients with sialorrhea and drooling
    Apostolopoulos, D.
    Cardenas, J.
    EUROPEAN JOURNAL OF NEUROLOGY, 2018, 25 : 209 - 209
  • [2] A 10-year Retrospective Review of Botulinum Toxin Injections and Surgical Management of Sialorrhea
    Weitzman, Rachel E.
    Kawai, Kosuke
    Nuss, Roger
    Hughes, Amy
    CUREUS JOURNAL OF MEDICAL SCIENCE, 2020, 12 (05)
  • [3] Botulinum Toxin A in the Management of Pediatric Sialorrhea: A Systematic Review
    Heikel, Tiffany
    Patel, Shivam
    Ziai, Kasra
    Shah, Sejal J.
    Lighthall, Jessyka G.
    ANNALS OF OTOLOGY RHINOLOGY AND LARYNGOLOGY, 2023, 132 (02): : 200 - 206
  • [4] Botulinum Toxin A in the Management of Pediatric Sialorrhea: A Systematic Review
    Berweck, Steffen
    ANNALS OF OTOLOGY RHINOLOGY AND LARYNGOLOGY, 2023,
  • [5] Botulinum toxin A in the treatment of sialorrhea
    Benson, Jennifer
    Daugherty, Kimberly K.
    ANNALS OF PHARMACOTHERAPY, 2007, 41 (01) : 79 - 85
  • [6] Therapy of sialorrhea with botulinum toxin
    Jost, Wolfgang H.
    Baeumer, Tobias
    Laskawi, Rainer
    Spittau, Bjoern
    Steffen, Armin
    Winterholler, Martin
    FORTSCHRITTE DER NEUROLOGIE PSYCHIATRIE, 2019, 87 (10) : 554 - 563
  • [7] Ultrasound-guided Botulinum Toxin-A Injections: A Method of Treating Sialorrhea
    Barbero, Pierangelo
    Busso, Marco
    Artusi, Carlo Alberto
    De Mercanti, Stefania
    Tinivella, Marco
    Veltri, Andrea
    Durelli, Luca
    Clerico, Marinella
    JOVE-JOURNAL OF VISUALIZED EXPERIMENTS, 2016, (117):
  • [8] Botulinum toxin in the treatment of sialorrhea
    Svetel, Marina
    Vasic, Milan
    Dragasevic, Natasa
    Pekmezovic, Tatjana
    Petrovic, Igor
    Kostic, Vladimir
    VOJNOSANITETSKI PREGLED, 2009, 66 (01) : 9 - 12
  • [9] Botulinum toxin in the treatment of sialorrhea
    Marina, Svetel
    Vasic, Milan
    Pekmezovic, Tatjana
    Kostic, Vladimir
    TOXICON, 2008, 51 : 50 - 50
  • [10] The effectiveness and safety of botulinum toxin injections for the treatment of sialorrhea with Parkinson's disease: a systematic review and meta-analysis
    Chun-Lan Yang
    Jia-Peng Huang
    Ying-chao Tan
    Ting-ting Wang
    Han Zhang
    Yun Qu
    BMC Pharmacology and Toxicology, 24