DIRECT RESOLUTION OF RACEMIC DRUGS USING CELLULASE SILICA AS A CHIRAL STATIONARY-PHASE

被引：7
|
作者：
BLOM, Y
HELDIN, E
机构：
[1] Medical Products Agency, Division of Pharmacy, S-75103 Uppsala
来源：
JOURNAL OF CHROMATOGRAPHY A | 1993年 / 653卷 / 01期
关键词：
D O I：
10.1016/0021-9673(93)80402-T
中图分类号：
Q5 [生物化学];
学科分类号：
071010 ; 081704 ;
摘要：
The enantiomers of propafenone, flecainide and its two analogues 4-hydroxyflecainide and 5-hydroxyflecainide, betaxolol, doxazosin, and terazosin and its analogue A-65297 were separated on a cellulase silica column (TrichSep-100). The effects of pH and the concentration of the organic modifier, 2-propanol, were studied.
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页码：138 / 143
页数：6
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