EFFICACY OF (-)-9-[4-HYDROXY-2-(HYDROXYMETHYL)BUTYL]GUANINE IN AFRICAN-GREEN MONKEYS INFECTED WITH SIMIAN VARICELLA VIRUS

被引：14
|
作者：
SOIKE, KF [1 ]
BOHM, R [1 ]
HUANG, JL [1 ]
OBERG, B [1 ]
机构：
[1] MEDIVIR AB,HUDDINGE,SWEDEN
来源：
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 1993年 / 37卷 / 06期
关键词：
D O I：
10.1128/AAC.37.6.1370
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
(-)-9-[4-Hydroxy-2-(hydroxymethyl)butyl]guanine was evaluated for its efficacy in African green monkeys infected with simian varicella virus. Treatment by intramuscular injection was initiated 48 h after virus inoculation and was continued for 10 days; the treatment showed therapeutic effects on rash and viremia at dosages down to 1 mg/kg of body weight per day.
引用
收藏
页码：1370 / 1372
页数：3
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