ANOMALOUS PH-DEPENDENCE OF KCAT-KM KM IN ENZYME REACTIONS - RATE CONSTANTS FOR ASSOCIATION OF CHYMOTRYPSIN WITH SUBSTRATES

被引：48

|

作者：

RENARD, M ^{[1
]}

FERSHT, AR ^{[1
]}

机构：

[1] UNIV CAMBRIDGE,POSTGRAD MED SCH,MRC,LAB MOLEC BIOL,CAMBRIDGE CB2 2QH,ENGLAND

来源：

BIOCHEMISTRY | 1973年 / 12卷 / 23期

关键词：

D O I：

10.1021/bi00747a026

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

收藏

页码：4713 / 4718

页数：6

相关论文

共 3 条

[1] PH-DEPENDENCE OF RATE CONSTANTS FOR REACTIONS OF CYTOCHROME-C WITH INORGANIC REDOX PARTNERS AND MECHANISTIC IMPLICATIONS
DRAKE, PL
HARTSHORN, RT
MCGINNIS, J
SYKES, AG
INORGANIC CHEMISTRY, 1989, 28 (07) : 1361 - 1366
[2] PH-DEPENDENCE OF 2ND-ORDER RATE CONSTANTS OF ENZYME MODIFICATION MAY PROVIDE FREE-REACTANT PKA VALUES
BROCKLEHURST, K
BIOCHEMICAL JOURNAL, 1977, 167 (03) : 859 - 862
[3] ALPHA-CHYMOTRYPSIN AND TRYPSIN CATALYZED-HYDROLYSIS OF AMINO-ACID ESTERS HAVING FREE ALPHA-AMINO GROUP - PH-DEPENDENCE OF INDIVIDUAL RATE CONSTANTS AND STEREOSPECIFICITY
KLYOSOV, AA
BIOORGANICHESKAYA KHIMIYA, 1977, 3 (11): : 1512 - 1522