RAPID-DETERMINATION OF PARACETAMOL IN BLOOD-SERUM SAMPLES BY FIRST-DERIVATIVE UV ABSORPTION-SPECTROSCOPY

被引：13
|
作者：
DAMIANI, PC
RIBONE, ME
OLIVIERI, AC
机构：
[1] Departamento de Química Analítica, Facultad de Ciencias Bioquímicas y Farmacéuticas, Universidad Nacional de Rosario, Suipacha
来源：
ANALYTICAL LETTERS | 1995年 / 28卷 / 12期
关键词：
DERIVATIVE UV SPECTROSCOPY; PARACETAMOL;
D O I：
10.1080/00032719508000040
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
A rapid method for the determination of paracetamol in human blood serum using first-derivative UV absorption spectroscopy is described. It involves no sample pretreatment, extraction or derivatization procedures, other than a standard deproteinizing technique with trichloroacetic acid. The results can be applied to both therapeutic and toxic levels of paracetamol.
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页码：2219 / 2226
页数：8
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