INTRODUCTION OF CARBOCYCLES AND HETEROCYCLES INTO SIDE-CHAIN OF ALPHA-TRIFLUOROMETHYL-SUBSTITUTED ALPHA-AMINO-ACIDS VIA DIELS-ALDER REACTION

被引：0
|
作者：
BURGER, K
GAA, K
MUTZE, K
机构：
来源：
CHEMIKER-ZEITUNG | 1991年 / 115卷 / 10期
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暂无
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Trifluoromethyl substituted alpha-amino acid derivatives 4, 5 having a diene function in the side chain are obtained on reaction of 5-fluoro-4-trifluoromethyl-oxazole 1 with allylic alcohols of the 3-hydroxypenta-1,4-diene type. Via 4 and 5 introduction of carbocyclic and heterocyclic systems into the side chain of alpha-amino acids can be achieved by [4 + 2] cycloaddition.
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页码：292 / 295
页数：4
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