Fast and accurate Monte Carlo modeling of a kilovoltage X-ray therapy unit using a photon-source approximation for treatment planning in complex media

被引:9
|
作者
Zeinali-Rafsanjani, B. [1 ]
Mosleh-Shirazi, M. A. [2 ,3 ]
Faghihi, R. [1 ,4 ]
Karbasi, S. [2 ]
Mosalaei, A. [2 ]
机构
[1] Shiraz Univ, Sch Mech Engn, Dept Med Radiat, Shiraz, Iran
[2] Shiraz Univ Med Sci, Dept Radiotherapy & Oncol, Shiraz 7193613311, Iran
[3] Shiraz Univ Med Sci, Radiol Res Ctr, Shiraz 7193613311, Iran
[4] Shiraz Univ, Sch Mech Engn, Radiat Res Ctr, Shiraz, Iran
关键词
Fast Monte Carlo; kilovoltage therapy; modeling of external therapy; treatment planning;
D O I
10.4103/0971-6203.158676
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
To accurately recompute dose distributions in chest-wall radiotherapy with 120 kVp kilovoltage X-rays, an MCNP4C Monte Carlo model is presented using a fast method that obviates the need to fully model the tube components. To validate the model, half-value layer (HVL), percentage depth doses (PDDs) and beam profiles were measured. Dose measurements were performed for a more complex situation using thermoluminescence dosimeters (TLDs) placed within a Rando phantom. The measured and computed first and second HVLs were 3.8, 10.3 mm Al and 3.8, 10.6 mm Al, respectively. The differences between measured and calculated PDDs and beam profiles in water were within 2 mm/2% for all data points. In the Rando phantom, differences for majority of data points were within 2%. The proposed model offered an approximately 9500-fold reduced run time compared to the conventional full simulation. The acceptable agreement, based on international criteria, between the simulations and the measurements validates the accuracy of the model for its use in treatment planning and radiobiological modeling studies of superficial therapies including chest-wall irradiation using kilovoltage beam.
引用
收藏
页码:74 / 79
页数:6
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