THE GENEXPRESS INDEX - A RESOURCE FOR GENE DISCOVERY AND THE GENIC MAP OF THE HUMAN GENOME

被引：74
|
作者：
HOULGATTE, R
MARIAGESAMSON, R
DUPRAT, S
TESSIER, A
BENTOLILA, S
LAMY, B
AUFFRAY, C
机构：
[1] CNRS, GENEXPRESS, UPR 420, F-94801 VILLEJUIF, FRANCE
[2] GENETHON, GENEXPRESS, F-91002 EVRY, FRANCE
来源：
GENOME RESEARCH | 1995年 / 5卷 / 03期
关键词：
D O I：
10.1101/gr.5.3.272
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Detailed analysis of a set of 18,698 sequences derived from both ends of 10,979 human skeletal muscle and brain cDNA clones defined 6676 functional families, characterized by their sequence signatures over 5750 distinct human gene transcripts. About half of these genes have been assigned to specific chromosomes utilizing 2733 eSTS markers, the polymerase chain reaction, and DNA from human-rodent somatic cell hybrids. Sequence and clone clustering and a functional classification together with comprehensive data base searches and annotations made it possible to develop extensive sequence and map cross-indexes, define electronic expression profiles, identify a new set of overlapping genes, and provide numerous new candidate genes for human pathologies.
引用
收藏
页码：272 / 304
页数：33
相关论文
共 50 条
  • [1] A gene map of the human genome
    Schuler, GD
    Boguski, MS
    Stewart, EA
    Stein, LD
    Gyapay, G
    Rice, K
    White, RE
    RodriguezTome, P
    Aggarwal, A
    Bajorek, E
    Bentolila, S
    Birren, BB
    Butler, A
    Castle, AB
    Chiannilkulchai, N
    Chu, A
    Clee, C
    Cowles, S
    Day, PJR
    Dibling, T
    Drouot, N
    Dunham, I
    Duprat, S
    East, C
    Edwards, C
    Fan, JB
    Fang, N
    Fizames, C
    Garrett, C
    Green, L
    Hadley, D
    Harris, M
    Harrison, P
    Brady, S
    Hicks, A
    Holloway, E
    Hui, L
    Hussain, S
    LouisDitSully, C
    Ma, J
    MacGilvery, A
    Mader, C
    Maratukulam, A
    Matise, TC
    McKusick, KB
    Morissette, J
    Mungall, A
    Muselet, D
    Nusbaum, HC
    Page, DC
    SCIENCE, 1996, 274 (5287) : 540 - 546
  • [2] Bioinformatics Assisted Gene Discovery and Annotation of Human Genome
    WANG Wei
    Chemical Research in Chinese Universities, 2002, (04) : 491 - 494
  • [3] Bioinformatics assisted gene discovery and annotation of human genome
    Wang, W
    Wang, YH
    Li, W
    CHEMICAL RESEARCH IN CHINESE UNIVERSITIES, 2002, 18 (04) : 491 - 494
  • [4] Human and mouse essentiality screens as a resource for disease gene discovery
    Pilar Cacheiro
    Violeta Muñoz-Fuentes
    Stephen A. Murray
    Mary E. Dickinson
    Maja Bucan
    Lauryl M. J. Nutter
    Kevin A. Peterson
    Hamed Haselimashhadi
    Ann M. Flenniken
    Hugh Morgan
    Henrik Westerberg
    Tomasz Konopka
    Chih-Wei Hsu
    Audrey Christiansen
    Denise G. Lanza
    Arthur L. Beaudet
    Jason D. Heaney
    Helmut Fuchs
    Valerie Gailus-Durner
    Tania Sorg
    Jan Prochazka
    Vendula Novosadova
    Christopher J. Lelliott
    Hannah Wardle-Jones
    Sara Wells
    Lydia Teboul
    Heather Cater
    Michelle Stewart
    Tertius Hough
    Wolfgang Wurst
    Radislav Sedlacek
    David J. Adams
    John R. Seavitt
    Glauco Tocchini-Valentini
    Fabio Mammano
    Robert E. Braun
    Colin McKerlie
    Yann Herault
    Martin Hrabě de Angelis
    Ann-Marie Mallon
    K. C.  Kent Lloyd
    Steve D. M. Brown
    Helen Parkinson
    Terrence F. Meehan
    Damian Smedley
    Nature Communications, 11
  • [5] Human and mouse essentiality screens as a resource for disease gene discovery
    Cacheiro, Pilar
    Munoz-Fuentes, Violeta
    Murray, Stephen A.
    Dickinson, Mary E.
    Bucan, Maja
    Nutter, Lauryl M. J.
    Peterson, Kevin A.
    Haselimashhadi, Hamed
    Flenniken, Ann M.
    Morgan, Hugh
    Westerberg, Henrik
    Konopka, Tomasz
    Hsu, Chih-Wei
    Christiansen, Audrey
    Lanza, Denise G.
    Beaudet, Arthur L.
    Heaney, Jason D.
    Fuchs, Helmut
    Gailus-Durner, Valerie
    Sorg, Tania
    Prochazka, Jan
    Novosadova, Vendula
    Lelliott, Christopher J.
    Wardle-Jones, Hannah
    Wells, Sara
    Teboul, Lydia
    Cater, Heather
    Stewart, Michelle
    Hough, Tertius
    Wurst, Wolfgang
    Sedlacek, Radislav
    Adams, David J.
    Seavitt, John R.
    Tocchini-Valentini, Glauco
    Mammano, Fabio
    Braun, Robert E.
    McKerlie, Colin
    Herault, Yann
    de Angelis, Martin Hrabe
    Mallon, Ann-Marie
    Lloyd, K. C. Kent
    Brown, Steve D. M.
    Parkinson, Helen
    Meehan, Terrence F.
    Smedley, Damian
    Ambrose, J. C.
    Arumugam, P.
    Baple, E. L.
    Bleda, M.
    Boardman-Pretty, F.
    NATURE COMMUNICATIONS, 2020, 11 (01)
  • [6] The human gene connectome as a map of short cuts for morbid allele discovery
    Itan, Yuval
    Zhang, Shen-Ying
    Vogt, Guillaume
    Abhyankar, Avinash
    Herman, Melina
    Nitschke, Patrick
    Fried, Dror
    Quintana-Murci, Lluis
    Abel, Laurent
    Casanova, Jean-Laurent
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2013, 110 (14) : 5558 - 5563
  • [7] THE HUMAN GENE CONNECTOME: A MAP OF SHORT CUTS FOR MORBID ALLELE DISCOVERY
    Itan, Y.
    Casanova, J-L.
    Abel, L.
    Zhang, S-Y.
    Quintana-Murci, L.
    Vogt, G.
    Abhyankar, A.
    JOURNAL OF CLINICAL IMMUNOLOGY, 2012, 32 : 383 - 383
  • [8] dbDNV: a resource of duplicated gene nucleotide variants in human genome
    Ho, Meng-Ru
    Tsai, Kuo-Wang
    Chen, Chun-houh
    Lin, Wen-chang
    NUCLEIC ACIDS RESEARCH, 2011, 39 : D920 - D925
  • [9] THE GENE MAP AND GENOME ORGANIZATION
    FREZAL, J
    JAPANESE JOURNAL OF HUMAN GENETICS, 1991, 36 (01): : 1 - 5
  • [10] THE GENE MAP AND GENOME ORGANIZATION
    FREZAL, J
    NOUVELLE REVUE FRANCAISE D HEMATOLOGIE, 1990, 32 (02): : 121 - 123
12345