A RELATIONAL DATABASE OF TRANSCRIPTION FACTORS

被引：193
作者：
GHOSH, D [1 ]
机构：
[1] HARVARD UNIV,SCH MED,DANA FARBER CANC INST,BOSTON,MA 02115
来源：
NUCLEIC ACIDS RESEARCH | 1990年 / 18卷 / 07期
基金：
美国国家卫生研究院;
关键词：
D O I：
10.1093/nar/18.7.1749
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Recent advances in the understanding of eukaryotic gene regulation have produced an extensive body of transcriptionally-related sequence information in the biological literature (1 - 8 for reviews), and have created a need for computing structures that organize and manage this information. The 'relational model' (9 - 11) represents an approach that is finding increasing application in the design of biological databases(l2 - 16). This report describes the compilation of information regarding eukaryotic transcription factors, the organization of this information into five tables, the computational applications of the resultant relational database that are of theoretical as well as experimental interest, and possible avenues of further development. © 1990 Oxford University Press.
引用
收藏
页码：1749 / 1756
页数：8
相关论文
共 77 条
[1]   GENE-REGULATION BY STEROID-HORMONES [J].
BEATO, M .
CELL, 1989, 56 (03) :335-344
[2]   CYTOSINE METHYLATION IN CTF AND SP1 RECOGNITION SITES OF AN HSV TK PROMOTER - EFFECTS ON TRANSCRIPTION INVIVO AND ON FACTOR BINDING INVITRO [J].
BENHATTAR, J ;
BEARD, P ;
JIRICNY, J .
NUCLEIC ACIDS RESEARCH, 1989, 17 (24) :10179-10190
[3]  
BICKNELL FJ, 1989, NUCLEIC ACIDS RES, V16, P1667
[4]  
BISHOP MJ, 1987, NUCLEIC ACID PROTEIN, P83
[5]   KNOWLEDGE-BASED PREDICTION OF PROTEIN STRUCTURES AND THE DESIGN OF NOVEL MOLECULES [J].
BLUNDELL, TL ;
SIBANDA, BL ;
STERNBERG, MJE ;
THORNTON, JM .
NATURE, 1987, 326 (6111) :347-352
[6]  
BONI J, 1989, J VIROL, V63, P4088
[7]  
Burks C, 1989, Proc Natl Acad Sci U S A, V86, P408, DOI 10.1073/pnas.86.2.408
[8]  
CARLBEREG K, 1988, J VIROL, V88, P1617
[9]  
CHIN R, 1989, CELL, V59, P979
[10]  
Codd E. F., 1979, ACM Transactions on Database Systems, V4, P397, DOI 10.1145/320107.320109
12345678