SYNTHESES AND X-RAY STUDIES OF DERIVATIVES OF 4-ACETYL-2-QUINOXALINONE - A REINVESTIGATION OF REACTIONS OF N,N'-BIS(CHLOROACETYL)-O-PHENYLENEDIAMINE WITH AMINES

被引：0

作者：

MIKICIUK-OLASIK, E

KAJKOWSKI, T

BARTCZAK, TJ

机构：

[1] TECH UNIV LODZ, INST GEN & ECOL CHEM,X-RAY CRYSTALLOG GRP,I-17, UL ZWIRKI 36, PL-90924 LODZ, POLAND

[2] MED UNIV LODZ, DEPT CHEM TECHNOL DRUGS, LODZ, POLAND

来源：

PHARMAZIE | 1993年 / 48卷 / 07期

关键词：

D O I：

暂无

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

The reaction of N,N'-bis(chloroacetyl)-o-phenylenediamine (1) with p-phenethidine gave 2-quinoxalinone (2) and N,N'-bis[2-(4-ethoxyphenyl)amino-1-oxoethyl]-o-phenylenediamine (3). In previous papers, the obtained cyclic compounds were wrongly described as derivatives of 2,3,4,5,6,7-hexahydro 1H-1,4,7-benzotriazonine [1]. As a result of intermolecular reaction of 1, 1,2-dihydro-2-quinoxalinone (4) and 1,2,3,4-tetrahydro-2-quinoxalinone (6) have been obtained. The structures of the compounds have been confirmed by the X-ray crystal structure analyses.

引用

页码：523 / 525

页数：3

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