INHALED METHACHOLINE DOES NOT INFLUENCE THE CELLULAR COMPOSITION OF BRONCHOALVEOLAR LAVAGE FLUID

被引：10
|
作者：
SODERBERG, M [1 ]
LUNDGREN, R [1 ]
BJERMER, L [1 ]
ANGSTROM, T [1 ]
机构：
[1] UMEA UNIV HOSP,DEPT CYTOL,S-90185 UMEA,SWEDEN
来源：
ALLERGY | 1993年 / 48卷 / 03期
关键词：
BRONCHOALVEOLAR LAVAGE; HISTAMINE TEST; METHACHOLINE TEST; LYMPHOCYTES; MAST CELLS;
D O I：
10.1111/j.1398-9995.1993.tb00709.x
中图分类号：
R392 [医学免疫学];
学科分类号：
100102 ;
摘要：
A methacholine or a histamine test is often used to quantitate bronchial responsiveness, in studies investigating the influence of various inhaled stimuli on the responsiveness and composition of bronchoalveolar lavage (BAL) fluid. Histamine has been shown to evoke an inflammatory cell response in BAL fluid. In order to test the influence of the methacholine test on the cellular composition of BAL fluid, we investigated 14 healthy, nonsmoking volunteers with a methacholine test 24 h before performing a BAL. The results showed no significant changes in the cellular composition of BAL fluid, as compared with control BAL in the same persons.
引用
收藏
页码：173 / 176
页数：4
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