Characterization of protein folding intermediates

被引：69

作者：

Dobson, Christopher M. ^{[1
]}

机构：

[1] Univ Oxford, Inorgan Chem Lab, South Pk Rd, Oxford OX1 3QR, England

来源：

CURRENT OPINION IN STRUCTURAL BIOLOGY | 1991年 / 1卷 / 01期

关键词：

D O I：

10.1016/0959-440X(91)90006-F

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Three complementary strategies have emerged for obtaining structural information about intermediate states in protein folding. These involve the characterization of species generated transiently during the refolding of denatured proteins, the study of stable partially folded states, and the design and study of peptide models of folding intermediates.

引用

页码：22 / 27

页数：6

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