Antifungal Potential of Propolis Against Carcinogenic Citrinin Produced by Aspergillus terreus Thom

A laboratory experiment was conducted to examine the propolis-induced changes on Aspergillus terreus as common producer of carcinogenic citrinin in seeds, feed, food and foodstuff. Keeping in view the attributes of growth criteria and citrinin production of A. terreus, propolis was very effective significantly in decreasing mold growth and mycotoxin production. The alterations in elements accumulation were negatively due to impact of propolis. The amino acids metabolism as key physio-biochemical attributes of fungal metabolism directly influenced by propolis negatively. The accumulation of both glutamic acid and proline due to propolis was observed, signalize to the activation of glutamate kinase followed by glutamine synthetase (for glutamic acid) and (3)-semialdehyde dehydrogenase (for proline), respectively. The alteration in amino acids metabolism indicated clearly too significant modifications in mold metabolic process towards catabolism.