POLYFUNCTIONAL INDOLE-3-CARBINOL DERIVATIVES - 1-(INDOL-3-YL)GLYCEROLS AND RELATED-COMPOUNDS, BETA-HYDROXYTRYPTAMINES AND ASCORBIGENS - CHEMISTRY AND BIOLOGICAL PROPERTIES

被引：0
|
作者：
PREOBRAZHENSKAYA, MN
KOROLEV, AM
ISAEVA, NN
LAZHKO, EI
LOMIDZE, LA
机构：
来源：
FARMACO | 1995年 / 50卷 / 06期
关键词：
D O I：
暂无
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
Earlier interaction of indole-3-carbinols with L-ascorbic acid and chemical and biological properties of formed 2-skatylderivatives of L-ascorbic acid (ascorbigens) were discussed. In this presentation the properties and stereochemistry of products of interaction of polyfunctional biologically important indole-3-carbinols (indoleglycerol analogs and beta-hydroxytryptamine derivatives) with L-ascorbic acid are investigated. Biological significance of this reaction is discussed.
引用
收藏
页码：369 / 377
页数：9
相关论文
共 7 条
  • [1] FISCHER INDOLE SYNTHESIS OF (BETA-OXO)INDOL-3-YL KETONES USING PROTECTED 1,3-DICARBONYL COMPOUNDS
    ZEPEDA, LG
    MORALESRIOS, MS
    JOSEPHNATHAN, P
    SYNTHETIC COMMUNICATIONS, 1992, 22 (22) : 3243 - 3256
  • [2] Cutaneous delivery of [1-(4-chloro-3-nitrobenzenesulfonyl)-1H-indol-3-yl]-methanol, an indole-3-carbinol derivative, mitigates psoriasiform lesion by blocking MAPK/NF-κB/AP-1 activation
    Weng, Jing-Ru
    Huang, Tse-Hung
    Lin, Zih-Chan
    Alalaiwe, Ahmed
    Fang, Jia-You
    BIOMEDICINE & PHARMACOTHERAPY, 2019, 119
  • [3] Targeting of the Akt-Nuclear Factor-κB Signaling Network by [1-(4-Chloro-3-nitrobenzenesulfonyl)-1H-indol-3-yl]-methanol (OSU-A9), a Novel Indole-3-Carbinol Derivative, in a Mouse Model of Hepatocellular Carcinoma
    Omar, Hany A.
    Sargeant, Aaron M.
    Weng, Jing-Ru
    Wang, Dasheng
    Kulp, Samuel K.
    Patel, Tushar
    Chen, Ching-Shih
    MOLECULAR PHARMACOLOGY, 2009, 76 (05) : 957 - 968
  • [4] LAMINARIBIOSE AS THE STARTING MATERIAL - FACILE SYNTHESIS OF BETA-(1-]3)-LINKED GAL-GAL DISACCHARIDE DERIVATIVES AND RELATED-COMPOUNDS
    WANG, LX
    SAKAIRI, N
    KUZUHARA, H
    JOURNAL OF CARBOHYDRATE CHEMISTRY, 1991, 10 (03) : 349 - 361
  • [5] [1-(4-chloro-3-nitrobenzenesulfonyl)-1H-indol-3-yl]-methanol, an indole-3-carbinol derivative, inhibits glutamate release in rat cerebrocortical nerve terminals by suppressing the P/Q-type Ca2+ channels and Ca2+/calmodulin/protein kinase A pathway
    Lu, Cheng Wei
    Lin, Tzu-Yu
    Yang, Hsiao Ching
    Hung, Chi Feng
    Weng, Jing Ru
    Chang, Der Chen
    Wang, Su Jane
    NEUROCHEMISTRY INTERNATIONAL, 2020, 140
  • [6] BENZOPHENONE RELATED-COMPOUNDS .6. SYNTHESIS AND BIOLOGICAL-ACTIVITY OF (3,5-DISUBSTITUTED-1H-1,2,4-TRIAZOL-1-YL)BENZOPHENONE DERIVATIVES
    HIRAI, K
    SUGIMOTO, H
    ISHIBA, T
    FUJISHITA, T
    TSUKINOKI, Y
    HIROSE, K
    JOURNAL OF HETEROCYCLIC CHEMISTRY, 1982, 19 (06) : 1363 - 1369
  • [7] STRUCTURAL STUDIES OF THE INTERACTION BETWEEN INDOLE-DERIVATIVES AND BIOLOGICALLY IMPORTANT AROMATIC-COMPOUNDS .11. X-RAY CRYSTALLOGRAPHIC, SPECTROSCOPIC, AND ENERGY CALCULATION STUDIES OF THE 3-CARBAMOYL-1-[3-(INDOL-3-YL)PROPYL]PYRIDINIUM ION, A CHARGE-TRANSFER INTERACTION-MODEL BETWEEN TRYPTOPHAN AND PYRIDINE COENZYMESIC
    ISHIDA, T
    IBE, S
    INOUE, M
    JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 2, 1984, (02): : 297 - 304
1