Utility of Y- and X-STRs in the research of complex biological relationship

被引：2

作者：

Builes, J. J. ^{[1
,2
]}

Manrique, A. ^{[1
,2
]}

Aguirre, D. ^{[1
]}

Puerto, Y. ^{[1
]}

Bravo, M. L. ^{[1
]}

Gusmao, L. ^{[3
]}

机构：

[1] Lab Genes Ltda, Carrera 48 10-45 Cons 611, Medellin, Colombia

[2] Univ Antioquia, Inst Biol, Medellin, Colombia

[3] Univ Porto, Inst Pathol & Mol Immunol, IPATIMUP, Oporto, Portugal

来源：

FORENSIC SCIENCE INTERNATIONAL GENETICS SUPPLEMENT SERIES | 2009年 / 2卷 / 01期

关键词：

X-STR; Y-STR; Relationship; DNA;

D O I：

10.1016/j.fsigss.2009.08.142

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

The social situation in the past years has led to increase in the paternity test with absent parents in Colombia. We present here three cases of biological relationship investigation of an extramarital son without parents; the first case is the biological relationship research between granddaughter and grandparents with dead parents, the second one is between niece and three paternal uncles without father and mother and the third one is between grandson and grandparents with dead parents. In the three cases the research started with the typification of 15 autosomal STRs markers. Cases 1 and 2 were complemented with X-STR markers and Case 3 was complemented with Y-STR haplotype, all cases were solved with a conclusive diagnosis. This report shows the efficiency of STRs markers linked to sexual chromosomes, like complement, when autosomal STRs are not allowed to get the necessary probability. (C) 2009 Elsevier Ireland Ltd. All rights reserved.

引用

页码：236 / 237

页数：2

共 7 条

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