Intraoperative ultrasound is associated with low re-excision rates following breast conserving surgery for non-palpable invasive breast cancers

Background: Wire localized breast biopsy (WLB) is the most commonly performed procedure for the removal of non-palpable breast cancer. It is associated with patient discomfort and high re-excision rates. Intraoperative ultrasound (IOUS) is an alternative technique that may improve patient experience and have lower re-excision rates. Methods: A retrospective, single surgeon experience with IOUS is compared with WLB. Case matching for variables known to impact re-excision rates is performed. Fisher's exact test was performed for categorical variables, and a T-test for continuous variables. Results: 28 patients underwent IOUS and WLB. Re-excision rates were the same in patients undergoing IOUS and WLB (10.7% vs 0%; p = 0.24). The calculated resection ratio was lower with IOUS than WLB (2.99 vs 3.46; p = 0.37), but did not reach statistical significance. Conclusion: In selected patients, intra-operative ultrasound can be performed with a favourable re-excision rate, and comparable amounts of tissue compared to wire localized breast biopsy. (C) 2021 Elsevier Inc. All rights reserved.