NUDT15 Variant in Thiopurine-Induced Leukopenia among Malaysian Patients with Inflammatory Bowel Disease

被引:0
|
作者
Wong, Shin Yee [1 ]
Lee, Way Seah [1 ]
Leow, Hwong Ruey [2 ]
Ng, Ruey Terng [1 ]
Hilmi, Ida Normiha [2 ]
机构
[1] Univ Malaya, Dept Paediat, Kuala Lumpur, Malaysia
[2] Univ Malaya, Dept Med, Kuala Lumpur, Malaysia
关键词
D O I
暂无
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
PP 0167
引用
收藏
页码:157 / 157
页数:1
相关论文
共 50 条
  • [21] ITPA polymorphisms do not predict additional risk beyond TPMT and NUDT15 for thiopurine-induced cytopenia in inflammatory bowel disease
    Jena, A.
    Grover, N.
    Bhatia, P.
    Singh, M.
    Lad, D.
    Prasad, K. K.
    Singh, H.
    Dutta, U.
    Sharma, V.
    REVISTA DE GASTROENTEROLOGIA DE MEXICO, 2024, 89 (01): : 25 - 30
  • [22] No increased risk for infections with thiopurine-induced leukopenia in inflammatory bowel disease patients without a variant in thiopurine S-methyltransferase
    Broekman, M.
    Coenen, M.
    van Marrewijk, C.
    Wanten, G.
    Derijks, L.
    Vermeulen, S.
    Wong, D.
    Klungel, O.
    Verbeek, A.
    Hooymans, P.
    Scheffer, H.
    Guchelaar, H. -J.
    de Jong, D.
    JOURNAL OF CROHNS & COLITIS, 2016, 10 : S247 - S247
  • [23] NUDT15 variants contribute to thiopurine-induced myelosuppression in European populations
    Walker, G.
    Harrison, J.
    Voskuil, M.
    Heap, G.
    Heerasing, N.
    Hendy, P.
    Koskela, J.
    Daly, M.
    Sokol, H.
    McGovern, D.
    Weersma, R.
    Bewshea, C.
    Weedon, M.
    Goodhand, J.
    Kennedy, N.
    Ahmad, T.
    JOURNAL OF CROHNS & COLITIS, 2018, 12 : S25 - S26
  • [24] NUDT15 VARIANTS CONTRIBUTE TO THIOPURINE-INDUCED MYELOSUPPRESSION IN EUROPEAN POPULATIONS
    Walker, Gareth J.
    Harrison, James W.
    Voskuil, Michiel D.
    Heap, Graham A.
    Heerasing, Neel
    Hendy, Peter J.
    Koskela, Jukka
    Daly, Mark J.
    Sokol, Harry
    Weersma, Rinse K.
    McGovern, Dermot
    Bewshea, Claire M.
    Weedon, Mike
    Goodhand, James
    Kennedy, Nicholas A.
    Ahmad, Tariq
    GASTROENTEROLOGY, 2018, 154 (06) : S111 - S111
  • [25] NUDT15 VARIANTS CONTRIBUTE TO THIOPURINE-INDUCED MYELOSUPPRESSION IN EUROPEAN POPULATIONS
    Walker, G. J.
    Harrison, J. W.
    Heap, G. A.
    Heerasing, N.
    Hendy, P. J.
    Bewshea, C.
    Goodhand, J. R.
    Weedon, M. N.
    Kennedy, N. A.
    Ahmad, T.
    GUT, 2017, 66 : A23 - A24
  • [26] Early Assessment of Thiopurine Metabolites Identifies Patients at Risk of Thiopurine-induced Leukopenia in Inflammatory Bowel Disease
    Wong, Dennis
    Coenen, Marieke
    Vermeulen, Sita
    Derijks, Luc
    van Marrewijk, Corine
    Klungel, Olaf H.
    Scheffer, Hans
    Franke, Barbara
    Guchelaar, Henk-Jan
    de Jong, Dirk
    Engels, Leopold
    Verbeek, Andr
    Hooymans, Piet
    JOURNAL OF CROHNS & COLITIS, 2017, 11 (02): : 175 - 184
  • [27] Diagnostic accuracy of NUDT15 gene variants for thiopurine-induced leukopenia: a systematic review and meta-analysis
    Cargnin, Sarah
    Genazzani, Armando A.
    Canonico, Pier Luigi
    Terrazzino, Salvatore
    PHARMACOLOGICAL RESEARCH, 2018, 135 : 102 - 111
  • [28] Plasma lipidomic profiling of thiopurine-induced leukopenia after NUDT15 genotype-guided dosing in Chinese IBD patients
    Li, Pan
    Chao, Kang
    Hu, Zhanhua
    Qin, Lulu
    Yang, Ting
    Mao, Jing
    Zhu, Xia
    Hu, Pinjin
    Wang, Xueding
    Gao, Xiang
    Huang, Min
    FRONTIERS IN NUTRITION, 2023, 10
  • [29] Prevalence of NUDT15 genetic variants and incidence of thiopurine-induced myelosuppression in inflammatory bowel disease: A systematic review and meta-analysis
    Yu, N.
    Sriranganathan, D.
    Walker, G.
    Sazonovs, A.
    Wilding, H.
    Roberts, C.
    Kennedy, N.
    Ahmad, T.
    Boyapati, R.
    Segal, J.
    Ding, J. N.
    JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 2023, 38 : 114 - 114
  • [30] NUDT15 VARIANT CAN PREDICT THE DEVELOPMENT OF AZATHIOPRINE INDUCED LEUKOPENIA AND ALLOW OPTIMAL DOSING IN INDIAN PATIENTS WITH INFLAMMATORY BOWEL DISEASE (IBD)
    Medaboina, Kavitha
    Banerjee, Rupa
    Vishnubhotla, Ravikanth
    Boramma, Ganesh Girish
    Gaddam, Narender
    Mitnala, Sasikala
    Duvvur, Nageshwar Reddy
    GUT, 2018, 67 : A88 - A89