Annual Meeting of the International Society of Cancer Metabolism (ISCaM): Metabolic Networks in Cancer

被引：6

作者：

Baldini, Nicola ^{[1
,2
]}

De Milito, Angelo ^{[3
]}

Feron, Olivier ^{[4
]}

Gillies, Robert J. ^{[5
]}

Michiels, Carine ^{[6
]}

Otto, Angela M. ^{[7
]}

Pastorekova, Silvia ^{[8
]}

Pedersen, Stine F. ^{[9
]}

Porporato, Paolo E. ^{[4
,10
]}

Sonveaux, Pierre ^{[4
]}

Supuran, Claudiu T. ^{[11
]}

Avnet, Sofia ^{[1
]}

机构：

[1] Rizzoli Orthopaed Inst, Bologna, Italy

[2] Univ Bologna, Dept Biomed & Neuromotor Sci, Bologna, Italy

[3] Karolinska Inst, Dept Oncol Pathol, Stockholm, Sweden

[4] Catholic Univ Louvain, IREC, Pole Pharmacol, Brussels, Belgium

[5] H Lee Moffitt Canc Ctr & Res Inst, Tampa, FL USA

[6] Univ Namur, Namur Res Inst Life Sci NARILIS, Namur, Belgium

[7] Tech Univ Munich, Munich Sch Bioengn, Munich, Germany

[8] Slovak Acad Sci, Biomed Res Ctr, Bratislava, Slovakia

[9] Univ Copenhagen, Dept Biol, Sect Cell Biol & Physiol, Copenhagen, Denmark

[10] Univ Torino, Mol Biotechnol Ctr, Dept Mol Biotechnol, Turin, Italy

[11] Univ Florence, Neurofarba Dept, Florence, Italy

来源：

FRONTIERS IN PHARMACOLOGY | 2017年 / 8卷

关键词：

tumor metabolism; proton dynamics; tumor microenvironment; cancer imaging; cancer therapy;

D O I：

10.3389/fphar.2017.00411

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Cancers are metabolic entities wherein cancer cells adapt their metabolism to their oncogenic agenda and microenvironmental influences. Metabolically different cancer cell subpopulations collaborate to optimize nutrient delivery with respect to immediate bioenergetic and biosynthetic needs. They can also metabolically exploit host cells. These metabolic networks are directly linked with cancer progression, treatment resistance and relapse. Conversely, metabolic alterations in cancer are exploited for anticancer therapy, imaging and personalized medicine. These topics were addressed at the 3rd annual meeting of the International Society of Cancer Metabolism (ISCaM) in Brussels, Belgium, on 26-29 October 2016.

引用

页数：5

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