The Waste Isolation Pilot Plant (WIPP) is a United States Department of Energy facility located in southeastern New Mexico. It is designed for the safe disposal of transuranic radioactive waste in deep geologic salt beds. Westinghouse TRU Solutions, LLC, the managing and operating contractor, undertook a project to simulate the processes at WIPP in order to identify bottlenecks and optimize available resources. The activities simulated in the model included the receipt, processing and disposal of radioactive waste underground, the mining of new areas for future waste disposal and the transportation of salt out of the mine. The complexity of the processes and the interactive requirements between processes required the use of advanced modeling techniques. The simulation model includes a huge number of locations and path network node points, with movement to and from the locations controlled using parameters rather than explicit routing. Information for the timing and sequence of the mining and nuclear waste emplacement operations is brought into the model via spreadsheets. Arrays in the simulation model keep track of past and future events that occur. Routing to the multiple possible positions in the underground mine is done using attributes and system functions within ProModel in order to allow for a highly flexible sequence of planned events and to reduce the level of effort in creating the ProModel processing. Considerable use of subroutines in the simulation model is utilized for parametric decision-making that is repetitive. This presentation describes the modeling techniques used to accurately simulate the surface and underground operations. The surface and underground operations are considerably different, thus they will be treated in their own sections.