Sulfur-33 nanoparticles: A Monte Carlo study of their potential as neutron capturers for enhancing boron neutron capture therapy of cancer

被引：22
|
作者：
Porras, I. [1 ]
机构：
[1] Univ Granada, Fac Ciencias, Dept Fis Atom Mol & Nucl, E-18071 Granada, Spain
来源：
APPLIED RADIATION AND ISOTOPES | 2011年 / 69卷 / 12期
关键词：
Neutron capture therapy; Epithermal neutrons; Sulfur nanoparticles; Monte Carlo simulation;
D O I：
10.1016/j.apradiso.2011.04.002
中图分类号：
O61 [无机化学];
学科分类号：
070301 ; 081704 ;
摘要：
In this paper, the potential effect of enhancing BNCT near the surface of the target volume by means of the addition of the sulfur isotope S-33 is studied. By means of Monte Carlo simulations, it is found a noticeable enhancement effect (local increase of the dose at the isotope site) when it is present at local concentrations that in principle can be reached by means of sulfur nanoparticles. A neutron beam with a high component of 13.5 keV would be required to produce this effect. Some open problems are discussed. (C) 2011 Elsevier Ltd. All rights reserved.
引用
收藏
页码：1838 / 1841
页数：4
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