Trigeminal neuralgia in a patient with multiple sclerosis and chronic inflammatory demyelinating polyneuropathy

Background: Trigeminal neuralgia (TN) is characterized by unilateral severe, brief, stabbing, recurrent pain in the distribution of one or more branches of the fifth cranial nerve. Syptomatic or secondary TN involves TN-pain that develops owing to a central nervous system lesion (benign or malignant) or to multiple sclerosis (MS). Case Description. The authors present a report of a unique case of a 43-year-old patient with unilateral TN, MS and concomitant chronic inflammatory demyelinating polyneuropathy. The facial pain preceded any other manifestations of the systemic disorders, and only after repeated neurological examinations were these diagnoses established. Clinical Implications. Magnetic resonance imaging of the brain and repeated neurological evaluations should be implemented in all patients with TN to rule out the presence of underlying disease. The dental practitioner should be familiar with TN to avoid unnecessary dental interventions and ensure prompt initiation of appropriate treatment.