A patient with valproic acid induced hyperammonaemic encephalopathy is presented. During chronic treatment with valproic acid this patient developed a potentially life-threatening encephalopathy without signs of liver failure. After discontinuing the valproic acid the patient recovered completely. In the case of a patient presenting with hyperammonaemic encephalopathy, the possibility of the use of valproic acid should not be overlooked.
机构:
Faulkner Hosp, Addict Med Serv, Addict Recovery Program, Boston, MA 02130 USAFaulkner Hosp, Addict Med Serv, Addict Recovery Program, Boston, MA 02130 USA
Starer, Jacquelyn
Chang, Grace
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机构:
Harvard Univ, Sch Med, Dept Psychiat, Boston, MA 02115 USA
Brigham & Womens Hosp, Dept Psychiat, Boston, MA 02115 USAFaulkner Hosp, Addict Med Serv, Addict Recovery Program, Boston, MA 02130 USA
Chang, Grace
AMERICAN JOURNAL OF DRUG AND ALCOHOL ABUSE,
2010,
36
(02):
: 98
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101