Efficient synthesis of 1,4-dihydronaphthalenelignans from 5-methylene-4-substituted-2(5H)-furanones and a concise synthesis of solafuranone

被引：12
|
作者：
Mahajan, VA [1 ]
Borate, HB [1 ]
Wakharkar, RD [1 ]
机构：
[1] Natl Chem Lab, Div Organ Chem, Pune 411008, Maharashtra, India
来源：
TETRAHEDRON | 2006年 / 62卷 / 06期
关键词：
lignans; furanones; exomethylene furanones; podophyllotoxin; dihydrotaiwanin; solafuranone;
D O I：
10.1016/j.tet.2005.10.054
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A short synthetic strategy for synthesis of lignan analogues involving 5-methylene-4-substituted-2(5H)-furanones as the key intermediates has been developed. Various lignans including the natural product solafuranone and analogues of dihydrotaiwanin C and deoxydehydropodophyllotoxin were synthesized in good yields. (c) 2005 Elsevier Ltd. All rights reserved.
引用
收藏
页码：1258 / 1272
页数：15
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