Metformin Antagonizes Radiotherapy-Induced Anti-Tumor Effects via Inhibition of cGAS-STING Pathway Mediated Immune Responses

被引:0
|
作者
Wu, M. [1 ]
Chen, D. [1 ]
Liu, Z. [1 ]
Chen, M. [1 ]
Liu, R. [1 ]
Wang, J. [1 ]
Li, X. [1 ]
Tao, Q. [1 ]
Yu, J. [1 ]
机构
[1] Shandong First Med Univ & Shandong Acad Med Sci, Shandong Canc Hosp & Inst, Jinan, Shandong, Peoples R China
关键词
D O I
暂无
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
2580
引用
收藏
页码:E268 / E268
页数:1
相关论文
共 50 条
  • [31] iNOS aggravates pressure overload-induced cardiac dysfunction via activation of the cytosolic-mtDNA-mediated cGAS-STING pathway
    Guo, Yongzheng
    You, Yuehua
    Shang, Fei-Fei
    Wang, Xiaowen
    Huang, Bi
    Zhao, Boying
    Lv, Dingyi
    Yang, Shenglan
    Xie, Ming
    Kong, Lingwen
    Du, Dingyuan
    Luo, Suxin
    Tian, Xin
    Xia, Yong
    THERANOSTICS, 2023, 13 (12): : 4229 - 4246
  • [32] Tumor-associated extracellular vesicles from HPV plus oropharyngeal cancer lymphatic fluid trigger an anti-tumor response through activation of the cGAS-STING pathway
    Xu, Zhongping
    Earland, Noah
    Harris, Peter K.
    Gerndt, Sophie P.
    Ramirez, Ricardo
    Semenkovich, Nicholas P.
    Chaudhuri, Aadel A.
    Zevallos, Jose P.
    CLINICAL CANCER RESEARCH, 2023, 29 (18)
  • [33] PhotoPyro-Induced cGAS-STING Pathway Activation Enhanced Anti-Melanoma Immunotherapy via a Manganese-Coordinated Nanomedicine
    Feng, Yuzhao
    Wang, Guohao
    Li, Wenxi
    Yan, Jie
    Yu, Xinying
    Tian, Hao
    Li, Bei
    Dai, Yunlu
    ADVANCED HEALTHCARE MATERIALS, 2024, 13 (06)
  • [34] WEE1 Inhibition Promotes Radiotherapy-Induced Myeloid Suppressor Cells through cGAS/STING-STAT3-IRF3 Pathway
    Hu, J.
    INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2023, 117 (02): : E236 - E236
  • [35] USP18 promotes innate immune responses and apoptosis in influenza A virus-infected A549 cells via cGAS-STING pathway
    Tang, Li
    Liu, Xi
    Wang, Ce
    Shu, Chang
    VIROLOGY, 2023, 585 : 240 - 247
  • [36] Inhibition of PLK4 remodels histone methylation and activates the immune response via the cGAS-STING pathway in TP53-mutated AML
    Man, Cheuk-Him
    Lam, Wing
    Dang, Chee-Chean
    Zeng, Xiao-yuan
    Zheng, Li-Chuan
    Chan, Natalie Nok-Man
    Ng, Ka-Lam
    Chan, Koon-Chuen
    Kwok, Tsz-Ho
    Ng, Timothy Chi-Chun
    Leung, Wing-Yan
    Huen, Michael Shing-Yan
    Wong, Carmen Chak-Lui
    So, Chi Wai Eric
    Dou, Zhixun
    Goyama, Susumu
    Bray, Mark Robert
    Mak, Tak Wah
    Leung, Anskar Yu-Hung
    BLOOD, 2023, 142 (23) : 2002 - 2015
  • [37] PRV infection triggers innate antiviral immune responses via cGAS-STING axis and TLR9-MyD88 axis mediated DNA-sensing signaling pathway
    He, X.
    Long, Z.
    Jia, H.
    Chen, G.
    Fang, Y.
    Wang, G.
    Jing, Z.
    EUROPEAN JOURNAL OF IMMUNOLOGY, 2019, 49 : 1078 - 1079
  • [38] Enhancement of anti-tumor immune responses induced by ligand-mediated biomimetic Texosomes
    Wang, Zhongyan
    Chang, Shasha
    Zhao, Xiuli
    Chen, Dawei
    Li, Kexin
    RSC ADVANCES, 2016, 6 (61) : 55819 - 55824
  • [39] Cytokine-Induced Senescence in the Tumor Microenvironment and Its Effects on Anti-Tumor Immune Responses
    Rentschler, Maximilian
    Braumueller, Heidi
    Briquez, Priscilla S.
    Wieder, Thomas
    CANCERS, 2022, 14 (06)
  • [40] Astragalus Polysaccharide Mitigates Rhabdomyolysis-Induced Acute Kidney Injury via Inhibition of M1 Macrophage Polarization and the cGAS-STING Pathway
    Sun, Chuanchuan
    Zhao, Xinhai
    Wang, Xianghong
    Yu, Yeye
    Shi, Heng
    Tang, Jun
    Sun, Shengyun
    Zhu, Shiping
    JOURNAL OF INFLAMMATION RESEARCH, 2024, 17 : 11505 - 11527